Drug sealing is an important step in ensuring the safety and effectiveness of drugs, and the following points must be strictly followed: 

1. Material compliance 

The sealing material must comply with pharmaceutical grade standards, such as USP Class VI, EP, or GMP certification, to ensure non toxicity and absence of precipitates. Aluminum foil sealing film or gasket should have excellent barrier properties to prevent oxygen, water vapor, and microbial invasion, especially for photosensitive drugs, light resistant materials should be selected. 

2. Sealing reliability 

The heat sealing parameters (temperature, pressure, time) need to be precisely controlled to avoid material degradation caused by excessive temperature or inadequate sealing caused by insufficient temperature. After sealing, a leak test (such as negative pressure method or dye penetration method) is required to ensure that there is no risk of leakage. 

3. Sterilization compatibility 

If the drug requires terminal sterilization (such as ethylene oxide, irradiation, or high-temperature steam), the sealing material must withstand the corresponding sterilization conditions. For example, radiation sterilization requires the use of radiation resistant adhesive layers to avoid aging and cracking. 

4. Anti counterfeiting and security 

Priority should be given to sealing designs with anti-counterfeiting features (such as destructive opening, QR code labels) to prevent tampering. For child safety packaging, it must comply with anti child opening standards such as ISO 8317. 

5. Production environment control 

Sealing operations should be carried out in a clean environment to avoid dust or microbial contamination. Automated equipment needs to be calibrated regularly to ensure consistency in sealing position and pressure. 

The quality of drug sealing directly affects product shelf life and medication safety. It is recommended to cooperate with professional suppliers to conduct sealing verification and stability testing to ensure compliance with global regulatory requirements.

The aluminum foil sealing film produced by Leadmens Packaging has many advantages such as strong sealing barrier, good tear off effect, bright colors, exquisite appearance, green environmental protection, high safety, strict testing, and stable quality. The effect is very reliable. If you are interested in or have any questions about us, please feel free to call us for consultation.